Contains botanical drawings with Mayan names on the recto of each leaf and descriptions of uses in Spanish on the verso. The description indicates the medical uses of each plant (use of the root to keep snakes away, etc.) and includes other data about the plant, such as aesthetic qualities, growth period, and classification. Written by a Franciscan friar of Campeche. The original ms. had at least 123 folios with herbal remedies described in alphabetical order. The manuscript was later rebound, probably in 1859, with 22 leaves extant (f. 81-84, 100-101, 107, 109, 112-114, 119-120, 123, and 3 leaves unidentified) and bound out of order.